https://my.ebook5.net/japanbioproductscoltd/fBVvxd2024/ # JBP Full Catalog 2024 ## Page 01 ![Page 01の画像](https://img01.ebook5.net/japanbioproductscoltd/fBVvxd2024/contents/image/book/medium/image-000001.jpg) 【ページ内のテキスト情報】 JapanBioProductsCo.,Ltd. ## Page 02 ![Page 02の画像](https://img01.ebook5.net/japanbioproductscoltd/fBVvxd2024/contents/image/book/medium/image-000002.jpg) 【ページ内のテキスト情報】 ## Page 03 ![Page 03の画像](https://img01.ebook5.net/japanbioproductscoltd/fBVvxd2024/contents/image/book/medium/image-000003.jpg) 【ページ内のテキスト情報】 1 ## Page 04 ![Page 04の画像](https://img01.ebook5.net/japanbioproductscoltd/fBVvxd2024/contents/image/book/medium/image-000004.jpg) 【ページ内のテキスト情報】 CORPORATEPROFILE2 ## Page 05 ![Page 05の画像](https://img01.ebook5.net/japanbioproductscoltd/fBVvxd2024/contents/image/book/medium/image-000005.jpg) 【ページ内のテキスト情報】 Placentainmother'swombprotectstheembryoandeventuallygrowingintofetus.Thistemporaryorgangivenexclusivelytothemammalianspeciesthroughanevolutionalprocessgeneratesvariousautacoids,whichareindispensabletothebirthofalifeanditsup-keep,andalsocontrolsthesignalsofgeneinformationtomakenewcells.Forthisreason,theplacentaiscalledthe“library”oflifeinformation.ItseffectiveutilizationhasbeenpracticedaroundtheworldsinceBCforthetreatmentofvariousdiseasesaswellastheup-keepofhealthandyouthfulness.AsBio-genometechnologieshasadvancedremarkablyinthismodernera,theideaoftheplacentautilizationgraduallydrawsattentiontothecuttingedgedomainofso-called“RegenerativeMedicine.”“Placenta”=“GreatBlessinggiventolife.”Foundedin1954inJapan,JapanBioProductsCo.,Ltd.(JBP)isaspecializedplacentacompanycoveringresearch,development,productionandmarketingpharmaceuticalproducts,supplementsandcosmeticsbasedonplacentalextracts.JBPisfurtherresponsibleinsolvingthequestionsstillpendingastothecompositionandmechanismofplacenta,andfortheeffectiveapplicationofvariousfeaturesofplacentainthesphereofmedicaltreatment,health,andbeautyculture.JBPhasalsobeeninvestingandresearchingmedicaldeviceswhichhavesynergisticeffectwithourvariousproductlines.Withastrongcommandofupdatedscientifictechnologies,JBPistheworldleadingcompanyintheareaofplacenta-basedproductstoday.3 ## Page 06 ![Page 06の画像](https://img01.ebook5.net/japanbioproductscoltd/fBVvxd2024/contents/image/book/medium/image-000006.jpg) 【ページ内のテキスト情報】 FunctionsofPlacentaTheplacentaisatemporaryorganwiththeroleofprotectingandnurturingababyinamother’swomb.Itservesasanaturalinterfaceforthesupplyofoxygenandnutrientsfromthemothertothebaby.Inorderforthebabytogrowhealthilywithinthewomb,theplacentaworksinarangeofwaysbyaidingindigestionandsecretioninplaceofinternalorgans,assistingwiththesecretionofhormones,andprovidinganimmunesystemforthedevelopingbaby.Placentaisalsoanorganthatsynthesizesandexcretes“cellgrowthfactor”,asubstancethatcontrolsthegrowthandreplicationofcells.Withoutcellgrowthfactoritisnotpossibletoproducenewcells.In10monthsofpregnancy,startingwithasinglecell,ababyisproducedwith40to60trillioncellsthankstothecellgrowthfactorproducedbytheplacenta.Placentaissomethingthatcomesaboutthroughtheseparationfromthesame,single,fertilizedovumasthebaby,givinggeneticinformationneededtoproduceallnecessarycells.Whenthebabyisfinallyborn,theplacenta’sroleiscompleted,anditisexpelledfromthebody.Despiteithasaccomplishedthemission,placentaisstillrichinnutrients,andcontainsallkindsofactiveingredients.Motheranimals,whohavetosurviveimmediatelyaftergivingbirth,andprotectthemselvesfromtheirenemies,recovertheirstrengthbyeatingtheplacenta,whichisrichinnutrients.Animalsmusthaveknowninstinctivelyaboutthepowerofplacenta.4 ## Page 07 ![Page 07の画像](https://img01.ebook5.net/japanbioproductscoltd/fBVvxd2024/contents/image/book/medium/image-000007.jpg) 【ページ内のテキスト情報】 SafetyCriteriaofJBPPlacentalExtract(Human)1.DonorScreening1)TestedNegativesforallvirus&bacteriatestsincludingHBV,HCV,HIV,Treponemapallidumetc.2)ScreeningofDonor’soverseasstayingexperience3)Donorconsenttouseasapharmaceuticalingredient2.AcceptanceInspectionTest1)Individualinspectionbyweight,color,smell,etc.2)NATtestingforHBV-DNA,HCV-RNA,HIV-1-RNAofallsamples.3.Sterilizationby3DifferentMethods1)Withorganicsolvent(acetone)2)Withdigestiveenzyme+acidprocessing3)With121℃×20minutesautoclave(finalsterilization)4.ProductSpecificationTestBeforeapprovedforshipment,theproductmustshow"negative"for:(1)HBV(2)HCV(3)HIV(4)HTLV(5)Parvovirus-B19JBPQualitySafetyCollectionofplacentasunderJapaneselaw.CredibilityMorethan50yearsinthemarketwithexcellentsafetystandard.ValidationThoroughandmultipleinspectionstoavoidcontamination.5 ## Page 08 ![Page 08の画像](https://img01.ebook5.net/japanbioproductscoltd/fBVvxd2024/contents/image/book/medium/image-000008.jpg) 【ページ内のテキスト情報】 NutritionalContentProteinsTheessentialnutrientsthatbuildaperson’sbodyandhelpmaintainthebody’sfunctions.CarbohydratesThesebecomeanimportantenergysourceandmaintainthestructureofthecells.ActivePeptidesThesearethekeyelementswithintheplacenta.Theyalsodemonstrateafavorableeffectwithinthebody.AminoAcidsTheessenceoflife.Hasvariousphysiologicalfunctionsforthehumanbody.6 ## Page 09 ![Page 09の画像](https://img01.ebook5.net/japanbioproductscoltd/fBVvxd2024/contents/image/book/medium/image-000009.jpg) 【ページ内のテキスト情報】 VitaminsAdjustsphysiologicalfunctionsandmakesmetabolismprocessatasmooth,reliablepace.LipidsandFattyAcidsTheseareoneoftheimportantmaterialsusedtomakecellsandkeepcellsstable.EnzymesTheenzymesassistwithintheplacentatohelpcreateandmaintainchemicalreactions.NucleicAcidEncode,transmitandexpressgeneticinformationwithinthehumanbody.Theycanalsoadjustmetabolism.MineralsMineralsplayvariousroles,suchasadjustingthelevelsofbloodandbiologicalfluids,etc.MucopolysaccharidesThesearetheelementswhichmaintainhealthycell-to-celljunctions.7 ## Page 10 ![Page 10の画像](https://img01.ebook5.net/japanbioproductscoltd/fBVvxd2024/contents/image/book/medium/image-000010.jpg) 【ページ内のテキスト情報】 LaennecInjectionisaprescriptiondrugmanufacturedwithJBP’suniquetechnologiesforeffectiveextractionofvarietyofgrowthfactors,cytokines,andotherphysiologicallyactivesubstancesfromthehumanplacenta.Forinstance,HGF(hepatocytegrowthfactor)promotestheproliferationofhepaticparenchymalcellsforrecoveryofadamagedliver.JBPhasestablishedatraceabilitysystemthatextendsfromtheproducttotherawmaterialsupplier,andconductedeveryprocessfromthecollectionofrawmaterialstothefinalproductionin-housetomaintainitstraceability.MainIndicationImprovementofhepaticfunctioninchronichepaticdisease.Composition112mgofhumanplacentahydrolysatein2mLampoule.PackageSize2mL×50ampoulesDosageandAdministrations.c.ori.m.(i.v.inprocess)injectionof1amp(2mL)oncedaily.Dosagecanbeincreasedto2or3timesdailyaccordingtosymptoms.PrecautionsMixturewithastrongbase>pH8.5attenuatespharmacologicalactivity.Placentainjectionwassuperiortoplaceboinpatientswithchronicliverdiseasesinadouble-blindcrossovercomparativestudy.1)Variousefficaciesandbenefitshavebeenreportedfromsomecountriesincludingimmunostimulatoryeffect,immunomodulatoryfunctions,andasfollowing;・ImprovementofsymptomsinCOVID-19viralinfections・ImprovementofQOL・Chronicfatiguesyndrome8・Infertilitytreatment・Woundrepair・Atopicdermatitis・Anti-aging1)“Placentainjectionwassuperiortoplaceboinpatientswithchronicliverdiseasesinadouble-blindcrossovercomparativestudy.”UedaH,etal.;Kanzo15(3):162-171,1974(Japanese) ## Page 11 ![Page 11の画像](https://img01.ebook5.net/japanbioproductscoltd/fBVvxd2024/contents/image/book/medium/image-000011.jpg) 【ページ内のテキスト情報】 CURACENCuracenisanethicaldrugforimprovingclimactericdisordersymptoms.ThisproductishydrolysateofHumanPlacentalExtractsbyHydrochloricacid.Thus,itsmolecularweightdistributionislessthan200Dalton.MainIndicationImprovementofclimactericdisordersymptoms.Composition100mgofhydrochloricacidprocessedhumanplacentahydrolysatein2mLampoule.Itisalightyellow-browntransparentliquid.ThepHlevelrangesfrom6.8to7.0andtheosmoticpressureratio(tophysiologicalsaline)isapproximatelyone.PackageSize2mL×50ampoulesDosageandAdministrationSubcutaneousinjectionof1amp.(2mL)3timesaweekfor2weeks.(total6times)Contentper2mLActiveingredientComponentContentRemarksWatersolublesubstanceextractedinthehydrolysisprocess.100mgComponentderivedformhumanplacentaInactiveingredientsBenzylalcoholpreservative0.03mLSoothingAgentJ-plaJ-plaisanethicaldrugtoimprovemenopausaldisordersymptomsaswellasanti-agingfunctionincludingwhitening,pigmentmaintenance,andanti-wrinkle.Duetoitshighskinpenetrationcapability,thereforeitisspecializedinbeauty/cosmeticpurposes.Composition50mgsolublesubstanceofhumanplacentahydrolysatein1mL.PackageSize2mL×50ampoulesDosageandAdministrationSubcutaneousinjectionof1amp.(2mL)3timesaweekfor2weeks.(total6times)9 ## Page 12 ![Page 12の画像](https://img01.ebook5.net/japanbioproductscoltd/fBVvxd2024/contents/image/book/medium/image-000012.jpg) 【ページ内のテキスト情報】 DIETARYSUPPLEMENTS10 ## Page 13 ![Page 13の画像](https://img01.ebook5.net/japanbioproductscoltd/fBVvxd2024/contents/image/book/medium/image-000013.jpg) 【ページ内のテキスト情報】 HealthisarelationshipbetweenyouandyourbodyDietarysupplementswhichmanufacturedundermeticulousobservationsofpharmaceuticalfacilitiesisanotheralternativemethodtoconsumeJBPPlacentalExtracthassle-free.JBP’sconstantpursuitofinnovationsincreatingPlacentalExtractproductsinvariousformsinordertofityourdailylifestyleaswellastosupportyourhealthandwellness.JBPAnimalPlacentaCollection100%collectedfromJBPcontractedfarms.RaisingmanagementbasedonJapanmeatstandards.S.O.P.ofPlacentacollectiontrainingbyJBPdedicatedstaff.Establishedtraceabilitysysteminordertotracethesourcefromproducttoranch.Everycollectedplacentawillbeissuedwithcertificateforqualityassurance.11 ## Page 14 ![Page 14の画像](https://img01.ebook5.net/japanbioproductscoltd/fBVvxd2024/contents/image/book/medium/image-000014.jpg) 【ページ内のテキスト情報】 100%HumanPlacentalsupplementextractedwiththesametechnologyandsafetyprotocolasLaennecInjection.IthasbeendesignedtocontainthesameefficacyandavailabilityasLaennecInjection.JBPhasbeenconductingcountlessresearchtasksonplacentasince1950’sandproducingPlacentalExtractsbothasmaterialandfinalproducts.Ourproductsincludemedicine,supplementsaswellascosmeticssince1970’sasthepioneertoutilizeplacentalextractiontechnology.SignificantvariationsariseintheconstituentsubstancesofPlacentalExtractsdependingontheextractionmethod.TheproductionmethodusedformanyPlacentalExtractsbreakdownpeptidesintosmallmolecularweightaminoacids.WhereasforJBP,wemanufacturewithauniqueextractiontechnologytoensurelargermoleculescontainedinplacentaremainintheextract.Thus,JBPPlacentalExtractcontainsgroupsofsubstanceswhichareexpectedtohavevariousphysiologicalactivities,includingaminoacids,lowmolecularweightpeptides,andhighmolecularweightpeptides.AlthoughLaennecP.O.isadietarysupplement,thePlacentalExtractusedismanufacturedusingthesameprocessasLaennecInjection,andisrecommendedbymedicalinstitutions,ormedicalpractitionersasanalternativetoLaennecInjectionforpatientswhoareunabletovisitthehospitaltoreceivetreatment.420mg×100caps/boxActiveIngredientsHumanPlacentalExtractDirectionsofUse2-6capsperday12 ## Page 15 ![Page 15の画像](https://img01.ebook5.net/japanbioproductscoltd/fBVvxd2024/contents/image/book/medium/image-000015.jpg) 【ページ内のテキスト情報】 CURACENP.O.+CuracenP.O.+isdesignedforthosewhoexperiencingphysicalchangesduetoaginganddesiretomaintaintheirinnerhealthaswellasyouthfulouterappearance.InadditiontoHumanPlacentalExtract(310mg/capsule),italsocontainsCystine(40mg/capsule)whichdemonstratesaverystrongantioxidanteffect,inhibitingthegrowthofmelanocytes.Therefore,itishighlyrecommendedforwomenwhoexpectrejuvenatingskinwithlesswrinklesandmorecollagenboostedbyCuracenP.O.+.ItisdesignedtocontainsimilarefficaciesastheCuraceninjection,withtwocapsulesequaltooneampoule.420mg×100caps/boxActiveIngredientsHumanPlacentalExtract,CystineDirectionsofUseForadults,take2capsulesdaily.Or2to6capsulesasneeded.CuracenP.O.+canbetakenbyitself,orwithanyotherdrugs/dietarysupplements,underthedirectionofaphysician.CautionStoreinacooldryplaceandconsumeassoonaspossibleafteropeningthealuminumpackage.13 ## Page 16 ![Page 16の画像](https://img01.ebook5.net/japanbioproductscoltd/fBVvxd2024/contents/image/book/medium/image-000016.jpg) 【ページ内のテキスト情報】 LAENNECP.O.PORCINEAcapsulecontains350mgof100%PorcinePlacentalExtract.ByapplyingJBP’suniquetechnologyandsafetyprotocol,thisproductwasdesignedforthoseinterestedinutilizingthehealthandnutritionalbenefitsofasupplement.Theproductisathighestquality,beingmanufacturedinourstate-of-the-artGMPfacility.350mg×100caps/boxActiveIngredientsPorcinePlacentalExtractDirectionsofUse3-6capsperday100%EquinePlacentalExtractdietarysupplement.PleaseenjoyonlythefinestadditivefreeEquinePlacentalExtractfromhorsesbredinJapan,beingmanufacturedinourstate-of-the-artGMPfacility.320mg×90caps/boxActiveIngredientsEquinePlacentalExtractDirectionsofUse3-4capsperday14 ## Page 17 ![Page 17の画像](https://img01.ebook5.net/japanbioproductscoltd/fBVvxd2024/contents/image/book/medium/image-000017.jpg) 【ページ内のテキスト情報】 EfficaciesonAgingCare/Dermatology(EfficacyofJBPPlacentalExtractonwrinklewidthsbelowtheeyeinclimactericwomen.)Retrospectively,atotalof123climactericwomenwithclimactericsymptomswereassignedtothreetreatmentgroups:notreatment(n=70),three350mgcapsulesofJBPPlacentalExtract(JPE)perdayfor12weeks(n=38),andsix350mgcapsulesofJPEperdayfor12weeks(n=15).After12weeksofJPEtreatment,thestudyfoundoutsignificantreductioninwrinklewidthsbelowtheeyeinsubjectswhotreatedwiththreecapsulesofJPEperday(p<0.05)andsubjectswhotreatedwithsixcapsulesofJPEperday(p<0.01),comparedwithuntreatedsubjects.SkinagingcarewithJBPPlacentalExtractThirty-twoadultwomenwhogaveconsentparticipatedthisstudy.Allreceiveda10mlbottleofplacentadrink,whichcontained360mgofJBPPlacentalExtract(JPE),dailyfor8weeks.Theyvisitedtheclinicwithin7daysbeforetheirmenstruationperiod,andrated21questionsfrom1to5(1:none,2:almostnone,3:little,4:moderate,5:severe)regardingtheirskincondition.Theyalsoassessedtheirphysicalcondition/fatiguewiththeVisualAnalogueScale(VAS).Thetotalskinconditionscorewaslowerafterconsumingtheplacentadrink.Inparticular,thescoresweresignificantlyimprovedasshownontherightchart.PotentialtoPreventAlzheimer'sDiseaseThestudiesshowedthatJBPPlacentalExtract(JPE),preventedtheonsetofmemorydysfunctionin5XFADmiceandenhancedneurogenesisanddendritedensityunderAβtreatment.Theextracthaspotentialasapreventivemedicinefordementia.EffectsoforaladministrationofJPEonobjectrecognitionmemorydeficitinyoung5XFADmiceFeedintakewith0.03%JPEsignificantlyimprovedtheabilityofobjectrecognitionmemory.Ahighdoseof3%JPEshowedanalmostsignificantupregulationofobjectrecognitionmemory.EffectsofJPEonAβ-inducedneuronallossanddendriteatrophyCellstreatedwithAβ25–35for4dayssignificantlydecreasedthenumberofneurons.ThesimultaneousadditionofJPEprotectedagainstneuronallossinadosedependentmanner.DendritelengthwasloweredbyAβ25–35treatment,andthe0.2,0.4,and2mg/mLJPEtreatmentssignificantlyincreaseddendritedensity.TheeffectsizesofJPEtreatmentweresufficientlylarge.*p<0.000115 ## Page 18 ![Page 18の画像](https://img01.ebook5.net/japanbioproductscoltd/fBVvxd2024/contents/image/book/medium/image-000018.jpg) 【ページ内のテキスト情報】 LNCPlacentaVCWhiteEachjellypouchcontains500mgofpureporcineplacentalextract.Themangoflavormakesiteasytoeat,andthepouchissmallenoughtobeconsumedbyitself,makingitaneasywaytoconsumeplacenta.20g×30pouches/boxActiveIngredientsPorcinePlacentalExtract,MangoPuree,ReducedSugarSyrup,Agar/TrehaloseDirectionsofUse1–3pouchesperday,chewingwellbeforeswallowingThishealthsupplementproductcontainshighpurityofPlacentalExtractPowder,VitaminC,andCystinetohelpimprovingskinconditionorpreventioninadvance.320mg×120tablets/bottleActiveIngredientsPorcinePlacentalExtract,Maltose/VitaminC,L-CystineDirectionsofUse3-4tabsperday16 ## Page 19 ![Page 19の画像](https://img01.ebook5.net/japanbioproductscoltd/fBVvxd2024/contents/image/book/medium/image-000019.jpg) 【ページ内のテキスト情報】 DIETARYSUPPLEMENTSFORPETSImage:Freepik.com17 ## Page 20 ![Page 20の画像](https://img01.ebook5.net/japanbioproductscoltd/fBVvxd2024/contents/image/book/medium/image-000020.jpg) 【ページ内のテキスト情報】 ForCatsandDogs100%PlacentalExtractPlacentalDietarySupplementsforPetsJBPPlacentaEQLiquidForPetsis100%liquidEquinePlacentalExtractobtainedfromhorsesbredinJapan.Twistoffthecapandgivetoyourpetasitis!JBPplacesgreatimportanceonusingnopreservativesoradditivesforthesafetyofyourpets.2mL×6tubes/boxActiveIngredientsLiquidEquinePlacentalExtractApplication1tube2~3timesaweekJBPPlacentaEQPowderForPetsis100%EquinePlacentalExtract,additivefree,inaneasilytwistablecapsule.Sprinklethecapsulecontentsoveryourpet’sfood,mixwell,anditisready!125mg×30caps/boxActiveIngredientsEquinePlacentalExtractApplication1capsuleperday,sprinkledon/mixedinfood18 ## Page 21 ![Page 21の画像](https://img01.ebook5.net/japanbioproductscoltd/fBVvxd2024/contents/image/book/medium/image-000021.jpg) 【ページ内のテキスト情報】 Questionnairebasedonanalysisofseniordogs/catswithSarcopeniaEvaluationbyVeterinariansSubjectswereobservedpositivechangeinmusclemassandstrengthimprovementby20-30%,whilenearly50%wasevaluatedas“slightlybetter”ormorebygeneralevaluation.【Musclemass】【Musclestrength】Althoughpositivechangeinmusclemassorstrengthwasonlyseenin20-30%ofanimals,nearly50%wasevaluatedas“slightlybetter”ormorebygeneralevaluation.BasedonJBPresearchdata.【Generalevaluation】Questionnairebasedonanalysisofseniordogs/catswithSarcopeniaEvaluationbyPetownersBothappetiteandactivitiesimprovedgraduallyin4weeks.Totallymorethan90%ofsubjectanimalsimprovedandmaintaintheappetiteandover80%withtheactivities.Asaresult,thesupplementisconsideredcontributestomaintainingQOLofSenioranimals.BasedonJBPresearchdata.【Appetite】【Activities】19 ## Page 22 ![Page 22の画像](https://img01.ebook5.net/japanbioproductscoltd/fBVvxd2024/contents/image/book/medium/image-000022.jpg) 【ページ内のテキスト情報】 SKINCARE20 ## Page 23 ![Page 23の画像](https://img01.ebook5.net/japanbioproductscoltd/fBVvxd2024/contents/image/book/medium/image-000023.jpg) 【ページ内のテキスト情報】 HumanPlacentalExtractstrengthenstheskinbarrierandrevealsbrighter,clearercomplexion.SkinTypeNormal,sensitiveRepairingCareProfessionalUseFormulatedbasedonHumanPlacentalExtractallowsanimmediatecellreactivationalongwithanicewhiteningandimprovementofskinglow.SkinTypeSuitableforanyskintypesBrighteningCareFormulatedwithantioxidantactivefactorsinEquinePlacentalExtractandhydrolysatewithVitaminC.SkinTypeNormaltocombination21 ## Page 24 ![Page 24の画像](https://img01.ebook5.net/japanbioproductscoltd/fBVvxd2024/contents/image/book/medium/image-000024.jpg) 【ページ内のテキスト情報】 MakeupRemoverCleansingLotionRepairingCareGHCHPSoapHP150mLLotionHP120mLBrighteningCareLNCCleansingBalm80gBrighteningSoap100gToningLotion/MoistureLotion120mLAnelaManaSoapMD5/MD10100g22 ## Page 25 ![Page 25の画像](https://img01.ebook5.net/japanbioproductscoltd/fBVvxd2024/contents/image/book/medium/image-000025.jpg) 【ページ内のテキスト情報】 SerumMoisturizerSunscreenSpecialCareEssenceHP3mLx5vialsCreamHP35gPlacental3DMaskwithCoQ105sheetsDiaserum35mLRepairingCream35gUVProtector40mLWrinkleEyeCream12gProfessionalUseCuracenEssence2mLx20vials23 ## Page 26 ![Page 26の画像](https://img01.ebook5.net/japanbioproductscoltd/fBVvxd2024/contents/image/book/medium/image-000026.jpg) 【ページ内のテキスト情報】 TheEffectofJBPPlacentalExtractonAnti-skinAgingActivity(A)H2O2CellViability(RatioofIntact)1.61.20.80.40IntactControlJPE(10μg/mL)JPE(100μg/mL)JPE(1000μg/mL)NAC(500μM)UVAH2O2(B)10080**p<0.01vs.Intactp<0.01vs.ControlTheanti-agingeffectofJBPPlacentalExtract(JPE)onthedermalfibroblastswasassessedandfoundthatitmarkedlysuppressedtheappearanceofβ-galactosidase-positivecellsamongthesenescentcellsinducedbyrepeatedhydrogenperoxideexposureorultravioletAirradiation.Moreover,theefficacyofJPEtreatmentwassimilartothatofanantioxidantN-acetylcysteine.Thus,owingtoitsantioxidanteffect,JPEcanbeusedasananti-agingagent,particularlyforthedermis.β-galpositivecell/totalcells6040200100806040200IntactControlJPE(100μg/mL)NAC(500μM)H2O2orUVA**p<0.01vs.Intactp<0.01vs.Control24 ## Page 27 ![Page 27の画像](https://img01.ebook5.net/japanbioproductscoltd/fBVvxd2024/contents/image/book/medium/image-000027.jpg) 【ページ内のテキスト情報】 TheEffectofJBPPlacentaExtractonAnti-inflammatoryandAnti-oxidantActivityoftheSkin(a)Control(b)DEM20μm(Nrf2Activator)(c)JPE4mg/ml**p<0.01*p<0.05vs.UVBTheanti-inflammatoryandanti-oxidanteffectofJBPPlacentalExtract(JPE)onepidermalkeratinocyteswasexamined.JPEreducedmRNAlevelsofTNF-α(TumorNecrosisFactor-α)andIL-6(Interleukin-6)amongtheinflammatorycytokinesreleasedbyepidermalkeratinocytesafterultravioletlight(UVB:290-320nm)exposure.JPEalsoactivatedNrf2,atranscriptionfactorknowntobeactivatedbyoxidativestresstopromotetheexpressionofantioxidantenzymesandsuppressinflammation,anditincreasedthemRNAleveloftheantioxidantenzymeHO-1(HemeOxygenase-1).TheseresultssuggestthatJPEsuppressesUV-inducedinflammationofepidermalkeratinocytesviaactivationofNrf2.**p<0.01vs.Intact25 ## Page 28 ![Page 28の画像](https://img01.ebook5.net/japanbioproductscoltd/fBVvxd2024/contents/image/book/medium/image-000028.jpg) 【ページ内のテキスト情報】 3BasicStepsRepairingCareGHCPlacentalCosmeticSeriesEffectivecellregenerationwithHumanPlacentalExtract.Placentalskincareproductsdirectlysolveskinproblems.JBPPlacentalExtractusedintheGHCCosmeticSeriesisextractedbythetechnologywedevelopedforpharmaceuticals.Frombrighteningandcolorbalancingtoantioxidantshelpingpurifytheskin,GHCHumanPlacentalExtractisaresourceforyouranti-agingneeds.1.CleansingGHCSoapHP150mLThisfacialsoapconsistsofFruit-derivedAHAgentlyyetthoroughlyremovesdirt,excessoil,andimpuritiestosupporthealthierskinturnover.TheluxuriouscleansingformulacontainsPlacentalExtract,4Nano-Vitamins,Chestnutextract,andrichinVitaminEhelpstopurifyandrevealsmoother,clearerskin.ActiveIngredients:PlacentalProtein,Squalane,AscorbylTetraisopalmitate,RetinylPalmitate,ArachisHypogaea(Peanut)Oil,Panthenol,CastaneaSativa(Chestnut)Extract,Lactobacillus/GrapeJuiceFermentFiltrate,Lactobacillus/PearJuiceFermentFiltrate,DipotassiumGlycyrrhizate26Image:Freepik.com ## Page 29 ![Page 29の画像](https://img01.ebook5.net/japanbioproductscoltd/fBVvxd2024/contents/image/book/medium/image-000029.jpg) 【ページ内のテキスト情報】 2.Hydration3.MoisturizingGHCLotionHPGHCCreamHP120mLThisLotionnotonlyhelpstuningchronobiologicalrhythmsbacktoanoptimallevel,PlacentalExtractandPomegranateFruitExtractwhichactasAnti-oxidantenhanceskinhydrationaswell.ActiveIngredients:PlacentalProtein,HydrolyzedCollagen,HydrolyzedHyaluronicAcid,SodiumHyaluronate,PolyglutamicAcid,CeramideNG,LepidiumSativumSproutExtract,PunicaGranatumFruitExtract,SodiumPCA,Oligopeptide-34,SodiumDilauramidoglutamideLysine35gThenaturalinter-cellularlipidscomprisedofLamellarliquidcrystalhelptorestoreskinmoisturebalance.WhileHyaluronicAcidandPlacentalExtractenrichelasticity,strengthentheskinbarrierandmaintainthebalanceofskinflora.ByaddingPrestigiousMandarinOrangePeelExtractwhichisrichinVitaminCcanfacilitatesoothingeffectontheskin.ActiveIngredients:PlacentalProtein,Coco-Caprylate/Caprate,OleaEuropaea(Olive)FruitOil,HydroxypropyltrimoniumHyaluronate,CitrusReticulata(Tangerine)PeelExtract,SolubleCollagen,SodiumRNA,Oligopeptide-34,LepidiumSativumSproutExtractImage:Freepik.comImage:Freepik.com27 ## Page 30 ![Page 30の画像](https://img01.ebook5.net/japanbioproductscoltd/fBVvxd2024/contents/image/book/medium/image-000030.jpg) 【ページ内のテキスト情報】 2SpecialSteps4.IntensiverepairingGHCEssenceHPEssence3mLx5vials/boxHighconcentrationofPlacentalExtract,CollagenandSodiumHyaluronatehelppromotingskinregeneration,reducingfinelines,improvingHyperpigmentationandsignsofage.Theskin-promotingingredientsenableintensiverepairingcarenotonlyathome,butalsorealizegreatereffectbyusingtogetherwithIontophoresistreatment.ActiveIngredients:PlacentalProtein,HydrolizedCollagen,SodiumHyaluronate28 ## Page 31 ![Page 31の画像](https://img01.ebook5.net/japanbioproductscoltd/fBVvxd2024/contents/image/book/medium/image-000031.jpg) 【ページ内のテキスト情報】 5.BoosterGHCPlacental3DMaskwithCoQ10FacialMask5sheetsThisfacialmaskwithneckpieceoffersintensivecarethroughExpressFacial,plusfacelinetreatmentinjust15minutes.Neckpiecewhichalsofullofpowerfulanti-oxidantPlacentalExtractenablefullcoveragefromfacetonecktoboostandrestoreskinelasticityaswellasbalancemoisturetoensureintenseandcontinuoushydration,therebyprovidingclearandradiantcomplexion.ActiveIngredients:PlacentalProtein,SodiumPCA,Polyquaternium-51,Ubiquinone29 ## Page 32 ![Page 32の画像](https://img01.ebook5.net/japanbioproductscoltd/fBVvxd2024/contents/image/book/medium/image-000032.jpg) 【ページ内のテキスト情報】 CLINICALRESULTImprovementofSkinConditionImproveskinbrightnessbyinhibitingTyrosinaseproduction.HelpsmoothingfinelinesbystimulatingCollagenproduction.Before5Sessions8SessionsAdminister2ml,subcutaneouslyonbothcheeksweekly.IncreaseHydrationtoprovideclearandradiant.TreatmentforThinningHairDuringtheclinicalstudies,forbothfemaleandmaletopofheadcaseswereremarkablyeffective.BeforeAfterBeforeAfterFollow-upImage:Freepik.comBeforeAfter(1month)(4monthsafter)30AdvisedbyShinichiSoyano,MD,Ph.D.SpecialistoftheJapanSocietyofPlasticandReconstructiveSurgerySpecialistandDirectoroftheJapanSocietyofAestheticPlasticSurgery ## Page 33 ![Page 33の画像](https://img01.ebook5.net/japanbioproductscoltd/fBVvxd2024/contents/image/book/medium/image-000033.jpg) 【ページ内のテキスト情報】 ForProfessionalUseOnly2mLx20vials/boxTakingadvantageofasmallermolecularweight(<200dalton)ofhumanplacentalextractsofCuracen,JBPhasdevelopedCuracenEssenceforspecificapplications.Smallermolecularweightisexpectedtohelppenetratedeepintotheskin.Successfullypairswithvirtualmesotherapy,iontophoresis,dermarollers,electroporationandderma-pens.ActiveIngredients:PlacentalExtractAdministrationEachCuracenEssenceissingleuseonly.FollowedbyusingGHCPlacental3DMaskwithCoQ10fortheoptimumeffect.ComponentofCURACENEssenceImage:Freepik.com31 ## Page 34 ![Page 34の画像](https://img01.ebook5.net/japanbioproductscoltd/fBVvxd2024/contents/image/book/medium/image-000034.jpg) 【ページ内のテキスト情報】 BrighteningCareLNCPlacentalSkinCareWhiteSeriesLNCPlacentalSkinCareWhiteseriesisaPlacentalExtract-basedskincaredesignedatJBP’spharmaceuticalgradefacilitytounleashtheskin-beautifyingeffectofplacentaatitsbest.ThehighestpossibleconcentrationofEquinePlacentalExtractoriginatedfromHokkaidoisformulatedinallitemsofthisseries.Besides,multipleactiveingredientsarecarefullyselectedandformulatedaccordingtovariouspurposesinordertoeffectivelyregularizeskintexture,improveskinbrightnessandtransformtohealthierskinbyprovidingskinelasticityandstrengthenskinbarrier.HealthcareProfessionals’UseExperienceSatisfactionAfterUseHopetoUseItAgain98%ofhealthcareprofessionalssaytheyaresatisfiedwiththeuseexperience.ExtremelySatisfied(46%)ModeratelySatisfied(42%)SlightlySatisfied(10%)SlightlyDissatisfied(1%)NoAnswer(1%)91%ofhealthcareprofessionalssaytheywoulduseitagain.VeryMuch(73%)QuiteaLot(18%)NotatAll(1%)NoAnswer(8%)·Respondents:doctors,nursesandmedicalinstitutionstaffinJapan(No.ofvalidrespondents:191)·SurveyTime:September2019·Surveyor:JapanBioProductsCo.,Ltd.32 ## Page 35 ![Page 35の画像](https://img01.ebook5.net/japanbioproductscoltd/fBVvxd2024/contents/image/book/medium/image-000035.jpg) 【ページ内のテキスト情報】 LNCCleansingBalmMakeupRemover80g/2.82ozLetthesoft&gentlebalmsetsaperfectfoundationCleansingistheveryfirstcrucialstepleadstonicelookingbareskinandpreparesafoundationforskincare.Asamakeupremover,LNCCleansingBalmisaskincare-inspiredcleansingproductwhichcombinescleansingandreducestheburdenontheskin,whilealsoleadstobrighteryetclearerskintone.ActiveIngredients:PlacentalProtein(Equine),CynaraScolymus(Artichoke)LeafExtract,3-O-EthylAscorbicAcid,GlucosylHesperidin,10-HydroxydecanoicAcid,SebacicAcid,1,10-Decanediol,HydrolyzedRoyalJellyProteinLNCBrighteningSoapFaceWashSoap100g/3.53ozBeautysoapfortrulyeffectivewashingcombinedwithagingcareApproximately50%ofthissoapismadeofingredientsthatbeautifyandmoisturizetheskin.Thepurewhitefoamisfineandsmooth,guaranteeingaluxuriouslyrefreshingmomentoffacecare.Suitableforallincludingeventhemostsensitiveskintype.ActiveIngredients:PlacentalProtein(Equine),Squalane,Polyquaternium-51,Ceramide333 ## Page 36 ![Page 36の画像](https://img01.ebook5.net/japanbioproductscoltd/fBVvxd2024/contents/image/book/medium/image-000036.jpg) 【ページ内のテキスト情報】 LNCToningLotionToner/SkinBooster120mL/4.06flozRetunesskintoanoptimumconditionforenhancedradianceandevenskintoneThisrefreshingskinlotionsoftenstheskinandprotectsitfromdamagingenvironmentalfactors.Italsoconditionstheskinsoastodrawoutitsnaturalbeautifultranslucence.ActiveIngredients:PlacentalProtein(Equine),3-O-EthylAscorbicAcid,AscorbylTetraisopalmitate,CentellaAsiaticaLeafExtract,CitrusNobilis(MandarinOrange)PeelExtract,SaxifragaSarmentosaExtract,LepidumSativumSproutExtract,CitrusJunosSeedOil,CoixLacryma-JobiMa-yuenSeedExtract,TocopherylNicotinate,CeramideNG,CeramideNP,CeramideAP,HydrolyzedCollagen,SolubleProteoglycan,SodiumHyaluronateLNCMoistureLotionMoisturizingSkinLotion120mL/4.06flozMoisturizingtheskininthewayitnaturallyretainsmoistureThishighlymoisturizingskinlotionreinforcestheskin’smoistureretentionintwoways,moisturiz-ingfromthesurfacedeeplyintothestratumcor-neumandsupportingtheskin’snaturalmoisturegeneration.ActiveIngredients:PlacentalProtein(Equine),PEG/PPG/PolybutyleneGlycol-8/5/3Glycerin,3-O-EthylAscorbicAcid,AscorbylTetraisopalmitate,CentellaAsiaticaLeafExtract,CoixLacryma-JobiMa-yuenSeedExtract,TremellaFuciformisPolysaccharide,Squalane,ButyrospermumParkii(Shea)Butter,TocopherylNicotinate,RetinylLinoleate,CeramideNP,CeramideAP,CeramideEOP,HydrolyzedCollagen,SolubleProteoglycan,SodiumHyaluronate34 ## Page 37 ![Page 37の画像](https://img01.ebook5.net/japanbioproductscoltd/fBVvxd2024/contents/image/book/medium/image-000037.jpg) 【ページ内のテキスト情報】 LNCDiaserumBeautySerum35mL/1.18flozBeautifulskinnow,fiveyearsfromnow,andeventenyearsfromnowDiaserumisabeautyserumcreatedexclusivelyforthepurposeofdelayingskinaging.Itseverydropispackedwithingredientsforagingcare.Thisserumisidealforlocalizedintensivecareandgeneralskincareformatureskin,aswellasforkeepingyoungerskinfreeofsignsofaging.ActiveIngredients:PlacentalProtein(Equine),Glycerin,SasaKurilensisWater,Hexyl3-GlycerylAscorbate,AcetylHexapeptide-8,Alpha-Arbutin,AvenaSativa(Oat)KeranelExtract,TremellaFuciformisPolysaccharideLNCWrinkleEyeCreamEyeCream12g/0.42ozSuitableforfinelinesaroundtheeyeswhereagingislikelytooccurLNCeyecreamadherestotheskinwithitsthicktexture.Thiscreammoisturizes,hydrates,andprovidessheercoverageofmoisture,firmness,andflexibilitytotheskinaroundtheeyesandotherareasshowingsignsofaging.ActiveIngredients:PlacentaProtein(Equine),Niacinamide,AscorbylTetraisopalmitate,DipotassiumGlycyrrhizate,CeramideNP,HydrolyzedHyaluronicAcid,SuccinoylAtelocollagen,HydrolyzedCollagen,Tocopherol,MelissaOfficinalisLeafExtract,MenthaPiperita(Peppermint)LeafExtract,GeraniumRobertianumExtract,MorindaCitrifoliaFruitJuice,LaminariaDigitataExtract,MalpighiaEmarginata(Acerola)FruitExtract,SolanumMelongena(Eggplant)FruitExtract,Alpha-GlucanOligosaccharide,CystoseiraTamariscifoliaExtract35 ## Page 38 ![Page 38の画像](https://img01.ebook5.net/japanbioproductscoltd/fBVvxd2024/contents/image/book/medium/image-000038.jpg) 【ページ内のテキスト情報】 LNCRepairingCreamSkinCream/EyeCream35g/1.23ozScientificallydesignedskincareintunewiththeskin’srebirthcycleWithitslamellastructureidenticaltothatoftheskin,thecreamprotectsandconditionstheskin,makingitporcelain-smoothandradiant.ActiveIngredients:PlacentalProtein(Equine),3-LaurylglycerylAscorbate,CeramideNG,CeramideNP,C12-13AlkylGlycerylHydrolyzedHyaluronate,SolubleProteoglycanLNCUVProtectorSunscreen40mL/1.35flozPowerfulUVprotectionofSPF50+PA++++with+++skincareeffectsGentleontheskin,thankstotheabsenceofUVabsorbents,andhighlyresistanttowaterandperspiration.ActiveIngredients:PlacentalProtein(Equine),ZincOxide,TitaniumDioxide,DipotassiumGlycyrrhizate36 ## Page 39 ![Page 39の画像](https://img01.ebook5.net/japanbioproductscoltd/fBVvxd2024/contents/image/book/medium/image-000039.jpg) 【ページ内のテキスト情報】 QUALITYSoap100gGlycolicacidhelpsexfoliateoverthekeratinofyourskintorevitalizeandbrightencomplexionswhilePlacentalExtractmoisturizesyourfaceandboostsskin’smetabolism.ManaSoapMD5with5%ofglycolicacidtoexfoliateyourfacegentlyorManaSoapMD10with10%glycolicacidtoexfoliateandpreventskinroughnessandimproveacne.ActiveIngredients:GlycolicAcid,Trehalose,BambooVinegar,CymbopogonSchoenanthusOil,SodiumAscorbylPhosphate,PlacentalProteinNaturalandHandmade–Itisourphilosophyandpride.ManaSoapMDishand-madeandemployed“ColdManufacturingProcess”thatisnaturaldryingmethod.Thismethodfeaturesnaturalmaturedprocesswithoutusinganyheat,whichavoidthedeteriorationoftheingredients.Asaresult,allactiveingredientsremainastheyare,andgentletoyourskin.Ingredients–Maximizingthehealingpowerofnature.NaturalFattyAcid(Vegetal)GlycolicAcidJBPPlacentalExtractCleaningIngredientCorneumSoftenerMoisturizingIngredientTrehaloseMoisturizingIngredientBambooVinegarSkinConditionerCymbopogonSchoenanthusOilNaturalPerfumeSodiumAscorbylPhosphateAntioxidantSubstanceNoticeablyReducesAcneScarsBefore-AcneScareAfter-14months37 ## Page 40 ![Page 40の画像](https://img01.ebook5.net/japanbioproductscoltd/fBVvxd2024/contents/image/book/medium/image-000040.jpg) 【ページ内のテキスト情報】 HeadquartersJapanBioProductsCo.,Ltd.1-44-4,Tomigaya,Shibuya-ku,Tokyo151-0063,JapanTEL:+81-3-3481-6061Fax:+81-3-3481-6065SatelliteOfficeGalerieVieTomigaya3F/4FMaplewood11Building,1-30-22,Tomigaya,Shibuya-ku,Tokyo151-0063,JapanTEL:+81-3-3481-6061Fax:+81-3-3481-6065PlantsL'AtelierFujimitsu735-14,AzaEdamitsu,Fujimitsumachi,Kurume,Fukuoka830-0054,JapanResearchandDevelopmentREBiotech.(IntraVentureCompany)2FKurumeResearchCenterBldg.,1-1Hyakunenkoen,Kurume-shi,Fukuoka,839-0864,JapanTechnologyDevelopmentCenterKurumeResearchCenterBldg.,1-1,Hyakunenkoen,Kurume,Fukuoka,839-0864,JapanGroupCompaniesGreenCrossWellBeingCorporation(Korea)JBPTaiwanCo.,Ltd.(Taiwan)JBPKoreaCo.,Ltd.(Korea)JBPChinaCo.,Ltd.(China)KurumePlant1493,Nonakamachi,Kurume,Fukuoka839-0862,JapanEumsungPlant156-50Naesong-ri,Geumwang-eup,Eumseong-gun,Chungcheongbuk-do,369-901,Korea38 ## Page 41 ![Page 41の画像](https://img01.ebook5.net/japanbioproductscoltd/fBVvxd2024/contents/image/book/medium/image-000041.jpg) 【ページ内のテキスト情報】 AuthorizedDistributorsAsiaMongoliaChina,TaiwanHongKong,MacauVietnamCambodiaThePhilippinesThailandIndonesiaMalaysiaDGBCo.,Ltd.LaennecBiotechCo.,Ltd.CosTherapyLtd.DucMinhMedicalJSC,AMVGroupL’espoirPharmaCo.,Ltd.Raquel-AbbasPharmaceuticals&GeneralMerchandiseBiogenetechCo.,Ltd.WorldHealthandBeautyProductsCo.,LtdInfiniteBeautyInternationalPteLtd(Singapore)ReyoungBeaute(M)SdnBhdCentralAsiaEuropeRussia,Armenia,Belarus,Kazakhstan,Kyrgyzstan,Moldova,Tajikistan,Turkmenistan,UzbekistanAzerbaijanGeorgiaUkraineRHANACorporationLLCPharmanovaLLCBeautySecretsInnovaestheticLtd.MiddleEastWestAsiaNorthAfricaSaudiArabiaBangladeshPakistan,AfghanistanUnitedArabEmiratesKuwaitJordanQatarOmanNorth,Central,SouthAmericaUnitedStatesMexicoDominicanRepublicDermaCityMedicalCompanyBioIngredientsLtd.StallionPharmaceuticals(Pvt)Ltd.NovanosParaPharmaceuticalProductsTradingL.L.C.CastilloInternationalGeneralTradingContractingCompanyLandofMedicineDrugstoreExpertDohaMedicalW.L.L.MedicalExperts'ServicesJBPGlobalUSADermavanMexicoSAdeCVGlobalSkinDominicana,S.R.L.39 ## Page 42 ![Page 42の画像](https://img01.ebook5.net/japanbioproductscoltd/fBVvxd2024/contents/image/book/medium/image-000042.jpg) 【ページ内のテキスト情報】 ## Page 43 ![Page 43の画像](https://img01.ebook5.net/japanbioproductscoltd/fBVvxd2024/contents/image/book/medium/image-000043.jpg) 【ページ内のテキスト情報】 ## Page 44 ![Page 44の画像](https://img01.ebook5.net/japanbioproductscoltd/fBVvxd2024/contents/image/book/medium/image-000044.jpg) 【ページ内のテキスト情報】 @japanbioproductshttp://jbpglobal.placenta.co.jp/